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TimeXNet Web - Identify active gene networks and pathways using time-course biological data

KEGG Pathway Enrichment

Job Name:
LPS Response in Mouse WT BMDCs
Current Gene List:
Background List:
Whole Genome
147 chart records
Note: Only the top 1000 records are shown here
Category Term Genes Count % P-value Benjamini
KEGG_PATHWAY mmu05142:Chagas disease (American trypanosomiasis)
73 5.9 2.4e-44 6.2e-42
KEGG_PATHWAY mmu05200:Pathways in cancer
150 12.1 1.3e-43 1.6e-41
KEGG_PATHWAY mmu04668:TNF signaling pathway
72 5.8 1.7e-40 1.4e-38
KEGG_PATHWAY mmu05164:Influenza A
89 7.2 1.9e-38 1.2e-36
KEGG_PATHWAY mmu04380:Osteoclast differentiation
75 6.0 1.2e-37 6.0e-36
KEGG_PATHWAY mmu04630:Jak-STAT signaling pathway
80 6.4 6.5e-37 2.8e-35
KEGG_PATHWAY mmu04620:Toll-like receptor signaling pathway
66 5.3 1.2e-36 4.3e-35
KEGG_PATHWAY mmu04722:Neurotrophin signaling pathway
72 5.8 8.5e-36 2.7e-34
KEGG_PATHWAY mmu05161:Hepatitis B
78 6.3 1.1e-34 3.2e-33
KEGG_PATHWAY mmu05169:Epstein-Barr virus infection
96 7.7 1.9e-34 4.8e-33
KEGG_PATHWAY mmu05205:Proteoglycans in cancer
92 7.4 1.3e-33 2.9e-32
KEGG_PATHWAY mmu04660:T cell receptor signaling pathway
64 5.1 2.7e-33 5.8e-32
KEGG_PATHWAY mmu05162:Measles
73 5.9 1.3e-32 2.6e-31
KEGG_PATHWAY mmu05160:Hepatitis C
73 5.9 1.3e-32 2.6e-31
KEGG_PATHWAY mmu05145:Toxoplasmosis
66 5.3 2.1e-32 3.8e-31
KEGG_PATHWAY mmu04010:MAPK signaling pathway
102 8.2 4.7e-32 8.0e-31
KEGG_PATHWAY mmu04012:ErbB signaling pathway
57 4.6 1.0e-31 1.7e-30
KEGG_PATHWAY mmu05220:Chronic myeloid leukemia
51 4.1 8.0e-31 1.2e-29
KEGG_PATHWAY mmu04510:Focal adhesion
89 7.2 2.1e-30 3.0e-29
KEGG_PATHWAY mmu04151:PI3K-Akt signaling pathway
120 9.7 8.0e-30 1.1e-28
KEGG_PATHWAY mmu04917:Prolactin signaling pathway
50 4.0 3.8e-29 4.8e-28
KEGG_PATHWAY mmu05166:HTLV-I infection
103 8.3 8.9e-29 1.1e-27
KEGG_PATHWAY mmu04062:Chemokine signaling pathway
84 6.8 1.4e-28 1.7e-27
KEGG_PATHWAY mmu04015:Rap1 signaling pathway
88 7.1 2.3e-28 2.6e-27
KEGG_PATHWAY mmu04068:FoxO signaling pathway
67 5.4 1.5e-27 1.6e-26
KEGG_PATHWAY mmu05212:Pancreatic cancer
45 3.6 1.6e-26 1.6e-25
KEGG_PATHWAY mmu04664:Fc epsilon RI signaling pathway
46 3.7 1.9e-26 1.8e-25
KEGG_PATHWAY mmu05203:Viral carcinogenesis
89 7.2 3.0e-26 2.8e-25
KEGG_PATHWAY mmu04064:NF-kappa B signaling pathway
55 4.4 4.0e-26 3.6e-25
KEGG_PATHWAY mmu04650:Natural killer cell mediated cytotoxicity
57 4.6 8.7e-26 7.7e-25
KEGG_PATHWAY mmu05152:Tuberculosis
75 6.0 2.5e-25 2.2e-24
KEGG_PATHWAY mmu05133:Pertussis
47 3.8 2.8e-25 2.3e-24
KEGG_PATHWAY mmu04210:Apoptosis
42 3.4 4.9e-25 3.9e-24
KEGG_PATHWAY mmu05215:Prostate cancer
51 4.1 7.9e-25 6.1e-24
KEGG_PATHWAY mmu05223:Non-small cell lung cancer
40 3.2 2.4e-24 1.8e-23
KEGG_PATHWAY mmu04014:Ras signaling pathway
84 6.8 4.1e-23 3.0e-22
KEGG_PATHWAY mmu04060:Cytokine-cytokine receptor interaction
87 7.0 7.8e-23 5.5e-22
KEGG_PATHWAY mmu04910:Insulin signaling pathway
62 5.0 5.1e-22 3.5e-21
KEGG_PATHWAY mmu05214:Glioma
41 3.3 6.8e-22 4.6e-21
KEGG_PATHWAY mmu04370:VEGF signaling pathway
39 3.1 1.7e-21 1.1e-20
KEGG_PATHWAY mmu04662:B cell receptor signaling pathway
42 3.4 2.9e-21 1.9e-20
KEGG_PATHWAY mmu04071:Sphingolipid signaling pathway
57 4.6 3.2e-21 2.0e-20
KEGG_PATHWAY mmu05140:Leishmaniasis
40 3.2 3.7e-21 2.3e-20
KEGG_PATHWAY mmu04915:Estrogen signaling pathway
50 4.0 4.2e-21 2.5e-20
KEGG_PATHWAY mmu05222:Small cell lung cancer
46 3.7 4.7e-21 2.8e-20
KEGG_PATHWAY mmu05168:Herpes simplex infection
76 6.1 8.0e-21 4.6e-20
KEGG_PATHWAY mmu05210:Colorectal cancer
39 3.1 4.4e-20 2.4e-19
KEGG_PATHWAY mmu04622:RIG-I-like receptor signaling pathway
39 3.1 8.1e-19 4.4e-18
KEGG_PATHWAY mmu04919:Thyroid hormone signaling pathway
51 4.1 1.3e-18 7.0e-18
KEGG_PATHWAY mmu04621:NOD-like receptor signaling pathway
35 2.8 1.6e-18 8.2e-18
KEGG_PATHWAY mmu04611:Platelet activation
55 4.4 2.7e-18 1.4e-17
KEGG_PATHWAY mmu04670:Leukocyte transendothelial migration
52 4.2 7.5e-18 3.8e-17
KEGG_PATHWAY mmu04914:Progesterone-mediated oocyte maturation
43 3.5 1.5e-17 7.5e-17
KEGG_PATHWAY mmu05213:Endometrial cancer
32 2.6 1.1e-16 5.6e-16
KEGG_PATHWAY mmu05221:Acute myeloid leukemia
33 2.7 2.0e-16 1.0e-15
KEGG_PATHWAY mmu04066:HIF-1 signaling pathway
46 3.7 2.0e-16 1.0e-15
KEGG_PATHWAY mmu05132:Salmonella infection
39 3.1 3.6e-16 1.6e-15
KEGG_PATHWAY mmu04912:GnRH signaling pathway
41 3.3 1.5e-15 6.4e-15
KEGG_PATHWAY mmu05231:Choline metabolism in cancer
43 3.5 1.3e-14 5.9e-14
KEGG_PATHWAY mmu05100:Bacterial invasion of epithelial cells
37 3.0 2.2e-14 9.3e-14
KEGG_PATHWAY mmu04923:Regulation of lipolysis in adipocytes
31 2.5 3.8e-14 1.6e-13
KEGG_PATHWAY mmu04810:Regulation of actin cytoskeleton
66 5.3 6.7e-14 2.8e-13
KEGG_PATHWAY mmu04931:Insulin resistance
44 3.5 8.8e-14 3.6e-13
KEGG_PATHWAY mmu04930:Type II diabetes mellitus
28 2.3 3.3e-13 1.3e-12
KEGG_PATHWAY mmu04666:Fc gamma R-mediated phagocytosis
37 3.0 3.6e-13 1.4e-12
KEGG_PATHWAY mmu04024:cAMP signaling pathway
60 4.8 2.0e-12 7.7e-12
KEGG_PATHWAY mmu05146:Amoebiasis
43 3.5 4.9e-12 1.9e-11
KEGG_PATHWAY mmu05202:Transcriptional misregulation in cancer
53 4.3 6.3e-12 2.4e-11
KEGG_PATHWAY mmu05321:Inflammatory bowel disease (IBD)
29 2.3 7.5e-12 2.8e-11
KEGG_PATHWAY mmu05211:Renal cell carcinoma
31 2.5 8.6e-12 3.2e-11
KEGG_PATHWAY mmu04261:Adrenergic signaling in cardiomyocytes
49 3.9 1.8e-11 6.5e-11
KEGG_PATHWAY mmu05134:Legionellosis
28 2.3 1.9e-11 6.8e-11
KEGG_PATHWAY mmu04932:Non-alcoholic fatty liver disease (NAFLD)
50 4.0 3.0e-11 1.1e-10
KEGG_PATHWAY mmu05218:Melanoma
31 2.5 5.2e-11 1.8e-10
KEGG_PATHWAY mmu05219:Bladder cancer
23 1.9 6.2e-11 2.1e-10
KEGG_PATHWAY mmu04110:Cell cycle
42 3.4 1.7e-10 6.0e-10
KEGG_PATHWAY mmu04640:Hematopoietic cell lineage
33 2.7 3.0e-10 1.0e-9
KEGG_PATHWAY mmu04520:Adherens junction
30 2.4 4.4e-10 1.5e-9
KEGG_PATHWAY mmu04540:Gap junction
33 2.7 6.1e-10 2.0e-9
KEGG_PATHWAY mmu04921:Oxytocin signaling pathway
47 3.8 1.6e-9 5.2e-9
KEGG_PATHWAY mmu04550:Signaling pathways regulating pluripotency of stem cells
43 3.5 1.9e-9 6.0e-9
KEGG_PATHWAY mmu04920:Adipocytokine signaling pathway
29 2.3 2.3e-9 7.2e-9
KEGG_PATHWAY mmu04960:Aldosterone-regulated sodium reabsorption
21 1.7 2.4e-9 7.5e-9
KEGG_PATHWAY mmu05230:Central carbon metabolism in cancer
27 2.2 2.8e-9 8.7e-9
KEGG_PATHWAY mmu04750:Inflammatory mediator regulation of TRP channels
40 3.2 4.2e-9 1.3e-8
KEGG_PATHWAY mmu04152:AMPK signaling pathway
40 3.2 5.4e-9 1.6e-8
KEGG_PATHWAY mmu04022:cGMP-PKG signaling pathway
47 3.8 2.5e-8 7.4e-8
KEGG_PATHWAY mmu04728:Dopaminergic synapse
40 3.2 2.9e-8 8.4e-8
KEGG_PATHWAY mmu04115:p53 signaling pathway
26 2.1 4.4e-8 1.3e-7
KEGG_PATHWAY mmu05014:Amyotrophic lateral sclerosis (ALS)
22 1.8 7.2e-8 2.1e-7
KEGG_PATHWAY mmu04623:Cytosolic DNA-sensing pathway
25 2.0 7.3e-8 2.1e-7
KEGG_PATHWAY mmu04360:Axon guidance
38 3.1 9.9e-8 2.8e-7
KEGG_PATHWAY mmu04144:Endocytosis
63 5.1 2.1e-7 5.9e-7
KEGG_PATHWAY mmu04150:mTOR signaling pathway
23 1.9 2.9e-7 7.9e-7
KEGG_PATHWAY mmu05340:Primary immunodeficiency
17 1.4 2.9e-7 7.9e-7
KEGG_PATHWAY mmu05143:African trypanosomiasis
17 1.4 4.7e-7 1.3e-6
KEGG_PATHWAY mmu04114:Oocyte meiosis
33 2.7 5.1e-7 1.4e-6
KEGG_PATHWAY mmu04730:Long-term depression
23 1.9 5.7e-7 1.5e-6
KEGG_PATHWAY mmu04350:TGF-beta signaling pathway
28 2.3 5.8e-7 1.5e-6
KEGG_PATHWAY mmu05144:Malaria
20 1.6 6.3e-7 1.6e-6
KEGG_PATHWAY mmu04530:Tight junction
38 3.1 7.8e-7 2.0e-6
KEGG_PATHWAY mmu04725:Cholinergic synapse
33 2.7 9.9e-7 2.5e-6
KEGG_PATHWAY mmu03050:Proteasome
19 1.5 1.0e-6 2.6e-6
KEGG_PATHWAY mmu04120:Ubiquitin mediated proteolysis
38 3.1 1.4e-6 3.4e-6
KEGG_PATHWAY mmu05020:Prion diseases
15 1.2 4.8e-6 1.2e-5
KEGG_PATHWAY mmu04141:Protein processing in endoplasmic reticulum
41 3.3 6.0e-6 1.5e-5
KEGG_PATHWAY mmu05323:Rheumatoid arthritis
25 2.0 1.2e-5 2.9e-5
KEGG_PATHWAY mmu05414:Dilated cardiomyopathy
25 2.0 1.5e-5 3.6e-5
KEGG_PATHWAY mmu04390:Hippo signaling pathway
37 3.0 1.7e-5 4.0e-5
KEGG_PATHWAY mmu05206:MicroRNAs in cancer
57 4.6 1.8e-5 4.1e-5
KEGG_PATHWAY mmu05030:Cocaine addiction
18 1.4 2.0e-5 4.6e-5
KEGG_PATHWAY mmu05416:Viral myocarditis
24 1.9 2.0e-5 4.6e-5
KEGG_PATHWAY mmu04720:Long-term potentiation
21 1.7 3.6e-5 8.3e-5
KEGG_PATHWAY mmu05216:Thyroid cancer
13 1.0 4.5e-5 0.0001
KEGG_PATHWAY mmu05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC)
21 1.7 0.00011 0.00026
KEGG_PATHWAY mmu04612:Antigen processing and presentation
23 1.9 0.00012 0.00026
KEGG_PATHWAY mmu04916:Melanogenesis
25 2.0 0.00032 0.00071
KEGG_PATHWAY mmu04145:Phagosome
37 3.0 0.00037 0.00082
KEGG_PATHWAY mmu05150:Staphylococcus aureus infection
16 1.3 0.00038 0.00083
KEGG_PATHWAY mmu05031:Amphetamine addiction
19 1.5 0.00047 0.001
KEGG_PATHWAY mmu04270:Vascular smooth muscle contraction
29 2.3 0.00057 0.0012
KEGG_PATHWAY mmu04672:Intestinal immune network for IgA production
14 1.1 0.00067 0.0014
KEGG_PATHWAY mmu04310:Wnt signaling pathway
31 2.5 0.00069 0.0014
KEGG_PATHWAY mmu04320:Dorso-ventral axis formation
10 0.8 0.0014 0.0028
KEGG_PATHWAY mmu05410:Hypertrophic cardiomyopathy (HCM)
20 1.6 0.0014 0.003
KEGG_PATHWAY mmu04940:Type I diabetes mellitus
17 1.4 0.0015 0.0031
KEGG_PATHWAY mmu04713:Circadian entrainment
23 1.9 0.0017 0.0034
KEGG_PATHWAY mmu04925:Aldosterone synthesis and secretion
21 1.7 0.0017 0.0034
KEGG_PATHWAY mmu04973:Carbohydrate digestion and absorption
13 1.0 0.0023 0.0046
KEGG_PATHWAY mmu05034:Alcoholism
38 3.1 0.0032 0.0063
KEGG_PATHWAY mmu05330:Allograft rejection
15 1.2 0.004 0.0079
KEGG_PATHWAY mmu04020:Calcium signaling pathway
34 2.7 0.0051 0.01
KEGG_PATHWAY mmu05332:Graft-versus-host disease
14 1.1 0.0055 0.011
KEGG_PATHWAY mmu04971:Gastric acid secretion
17 1.4 0.0076 0.015
KEGG_PATHWAY mmu04330:Notch signaling pathway
13 1.0 0.0089 0.017
KEGG_PATHWAY mmu04512:ECM-receptor interaction
19 1.5 0.012 0.022
KEGG_PATHWAY mmu04918:Thyroid hormone synthesis
16 1.3 0.013 0.025
KEGG_PATHWAY mmu04723:Retrograde endocannabinoid signaling
21 1.7 0.014 0.026
KEGG_PATHWAY mmu04970:Salivary secretion
17 1.4 0.014 0.027
KEGG_PATHWAY mmu04924:Renin secretion
15 1.2 0.032 0.059
KEGG_PATHWAY mmu04514:Cell adhesion molecules (CAMs)
28 2.3 0.034 0.061
KEGG_PATHWAY mmu04961:Endocrine and other factor-regulated calcium reabsorption
12 1.0 0.034 0.062
KEGG_PATHWAY mmu04724:Glutamatergic synapse
21 1.7 0.042 0.075
KEGG_PATHWAY mmu04913:Ovarian steroidogenesis
12 1.0 0.062 0.11
KEGG_PATHWAY mmu04922:Glucagon signaling pathway
18 1.4 0.069 0.12
KEGG_PATHWAY mmu05032:Morphine addiction
17 1.4 0.07 0.12
KEGG_PATHWAY mmu04911:Insulin secretion
16 1.3 0.07 0.12